Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight ...

(CE) and methionine restriction (MetR) impacts health and leads to weight loss in mice. The authors provided valuable datasets showing that the responses to MR and CE are tissue-specific, while MR and ...

A comprehensive, multi-phase investigation published in Advanced Science suggests that the amino acid tryptophan (Trp) may be a key determinant of therapeutic response to conventional synthetic ...

Alida Biosciences’ EpiPlex platform uses robust assay controls and specialized bioinformatics to detect RNA modification, genomic coordinates, and relative quantity.

Investigators have developed a prognostic model that may identify which patients with MIBC are suitable for bladder-preserving chemoradiation.

This interesting study adapts machine learning tools to analyze movements of a chromatin locus in living cells in response to serum starvation. The machine learning approach developed is useful, the ...

One such protein, Bromodomain and PHD finger-containing protein 1b (BRPF1b), regulates transcription through multiple chromatin reader domains—including a double PHD and zinc finger assembly, a ...

This study reveals that glycine decarboxylase (GLDC) promotes IgA nephropathy (IgAN) progression by enhancing mesangial cell ...

An epigenome-wide study uncovers ancestry-associated DNA methylation reprogramming in African prostate tumours, implicating enhancer dysregulation and developmental pathway activation in aggressive ...

Biogen has discontinued all gene therapy programs using adeno-associated virus (AAV) capsids, instead shifting resources to modalities that have the highest likelihood of achieving better treatment ...