Real-World Overall Survival and Treatment Patterns by PTEN Status in Metastatic Castration-Resistant Prostate Cancer Poly(ADP-ribose) polymerase inhibitors (PARPi) have shown promising clinical ...
Researchers have identified the exact DNA sequence where human chromosomes fuse to form Robertsonian chromosomes, a ...
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Boosting precision gene editing: Autophagy shifts DNA repair toward homologous recombination
Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...
Safety and Activity of Fibroblast Growth Factor Receptor Inhibitors in Advanced Malignancies: A Pooled Analysis of Early-Phase Clinical Trials Fourteen patients were accrued to the trial, which was ...
Researchers from the Universitat Autònoma de Barcelona (UAB) have published an analysis that reveals new functions of the ...
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Evolutionary mutation in cGAS enhances naked mole-rat DNA repair
The secret to the naked mole-rats' extraordinarily long life may lie in subtle changes to just four amino acids, researchers ...
Potential first-in-class, and industry-leading DNA polymerase Theta (Polθ) inhibitor, ART6043 demonstrated an attractive tolerability profile, expected PK/PD activity, and promising clinical ...
Scientists in Helsinki studied nearly 400 dog families to see how new DNA mutations arise in puppies. They found that older ...
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