Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can ...

Unlike patients presenting at diagnosis with major route karyotypes of chronic myeloid leukemia (CML), those presenting with balanced or unbalanced minor route karyotype do not suffer worse prognosis ...

Translocations occur in a proportion of couples affected by recurrent miscarriages. We describe two such families in which the underlying cause was a cryptic subtelomeric 11p;17p translocation ...

The abundant chromosome abnormalities in most carcinomas are probably a reflection of genomic instability present in the tumor, so the pattern and variability of chromosome abnormalities will reflect ...